Ganoderma lucidum
Reishi mushroom is a functional fungus usedin traditional Chinese medicine for over 2,000 years, often referred to as the“mushroom of immortality.” Unlike culinary mushrooms, it is valued primarilyfor its bioactive compounds rather than macronutrient content.
Modern research highlights Reishi’s role in immune modulation, inflammationcontrol, and antioxidant defence. It is particularly relevant to longevity dueto its effects on chronic inflammation and immune ageing (immunosenescence).
Reishi is not a significant source of macronutrients but is rich in bioactive compounds:
- Beta-glucans (polysaccharides) – immune modulation
- Triterpenes (ganoderic acids) – anti-inflammatory and antioxidant
- Peptidoglycans – support immune signalling
- Sterols – contribute to cellular and metabolic processes
Reishi helps regulate immune activity rather than overstimulating it.Beta-glucans enhance NK cell activity.
Helps suppress pro-inflammatory cytokines and modulate NF-κB pathways.
Reduces oxidative stress and cellular damage.
Acts as an adaptogen supporting stress response and sleep.
Review
Pharmacological potential was observed in diabetes, inflammation, epilepsy, neurodegeneration, cancer, anxiety, sedation, cardiac diseases, depression, hepatic diseases, and immune disorders
View on PubMed →Randomised controlled trial · Adults with metabolic risk factors
Reishi possess potential anti-cancer activity through immunomodulatory, anti-proliferative, pro-apoptotic, anti-metastatic and anti-angiogenic effects
View on PubMed →Sea buckthorn is a highly nutrient-dense ingredient with evidence supporting its role in skin health, cardiovascular function, inflammation reduction, and metabolic health. Its unique omega-7 content and antioxidant profile make it a valuable addition to a longevity-focused formulation.
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